Article
Mutational signature analysis in non-small cell lung cancer patients with a high tumor mutational burden.
Respiratory research - 24 Nov 2021
van den Heuvel Guus R M, Kroeze Leonie I, Ligtenberg Marjolijn J L, Grünberg Katrien, Jansen Erik A M, von Rhein Daniel, de Voer Richarda M, van den Heuvel Michel M
Abstract excerpt
BACKGROUND: Lung cancer is the leading cause of cancer death worldwide. With the growing number of targeted therapies and the introduction of immuno-oncology (IO), personalized medicine has become standard of care in patients with metastatic disease. The development of predictive and prognostic biomarkers is of great importance. Mutational signatures harbor potential clinical value as predictors of therapy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.