Article
Somatic Mutation Spectrum of Non-Small-Cell Lung Cancer in African Americans: A Pooled Analysis.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2015
Araujo Luiz H, Lammers Philip E, Matthews-Smith Velmalia, Eisenberg Rosana, Gonzalez Adriana, Schwartz Ann G, Timmers Cynthia, Shilo Konstantin, Zhao Weiqiang, Natarajan Thanemozhi G, Zhang Jianying, Yilmaz Ayse Selen, Liu Tom, Coombes Kevin, Carbone David P
Abstract excerpt
INTRODUCTION: The mutational profile of non-small-cell lung cancer (NSCLC) has become an important tool in tailoring therapy to patients, with clear differences according to the population of origin. African Americans (AAs) have higher lung cancer incidence and mortality than Caucasians, yet discrepant results have been reported regarding the frequency of somatic driver mutations. We hypothesized that NSCLC has a...
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