Article
High tumor mutation burden predicts favorable outcome among patients with aggressive histological subtypes of lung adenocarcinoma: A population-based single-institution study.
Neoplasia (New York, N.Y.) - 1 Sept 2020
Talvitie Eva-Maria, Vilhonen Heikki, Kurki Samu, Karlsson Antti, Orte Katri, Almangush Alhadi, Mohamed Hesham, Liljeroos Lassi, Singh Yajuvinder, Leivo Ilmo, Laitinen Tarja, Kallajoki Markku, Taimen Pekka
Abstract excerpt
OBJECTIVES: Tumor mutation burden (TMB) is an emerging predictive cancer biomarker. Few studies have addressed the prognostic role of TMB in non-small cell lung carcinoma, with conflicting results. Moreover, the association of TMB with different histological subtypes of lung adenocarcinoma has hitherto not been systematically evaluated. Here we studied the prognostic value of TMB and its distribution in different...
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