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Article

Aggregation of high-frequency RBD mutations of SARS-CoV-2 with three VOCs did not cause significant antigenic drift.

Journal of medical virology - 1 May 2022

Li Tao, Cui Zhimin, Jia Yunfei, Liang Ziteng, Nie Jianhui, Zhang Li, Wang Meng, Li Qianqian, Wu Jiajing, Xu Nan, Liu Shuo, Li Xueli, An Yimeng, Han Pu, Zhang Mengyi, Li Yuhua, Qu Xiaowang, Wang Qihui, Huang Weijin, Wang Youchun

Abstract excerpt

Variants of SARS-CoV-2 continue to emerge, posing great challenges in outbreak prevention and control. It is important to understand in advance the impact of possible variants of concern (VOCs) on infectivity and antigenicity. Here, we constructed one or more of the 15 high-frequency naturally occurring amino acid changes in the receptor-binding domain (RBD) of Alpha, Beta, and Gamma variants. A single mutant of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35032057
DOI: 10.1002/jmv.27596
PMCID: PMC9015629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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