Article

Reduced neutralization of SARS-CoV-2 B.1.617 variant by inactivated and RBD-subunit vaccine

2021-07-09

Abstract excerpt

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The Spike protein that mediates coronavirus entry into host cells is a major target for COVID-19 vaccines and antibody therapeutics. However, multiple variants of SARS-CoV-2 have emerged, which may potentially compromise vaccine effectiveness. Using a pseudovirus-based assay, we evaluated SARS-CoV-2 cell...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 70925bc7-3710-54aa-a81e-8e86b73b6b43
DOI: 10.1101/2021.07.09.451732

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Reduced neutralization of SARS-CoV-2 B.1.617 variant by inactivated and RBD-subunit vaccineDOI 10.1101/2021.07.09.451732Read

SARS-CoV-2 Variant B.1.1.7 is Susceptible to Neutralizing Antibodies Elicited by Ancestral Spike VaccinesSemantic proximity Read

SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines.Semantic proximity Read

Ad26.COV2.S elicited neutralizing activity against Delta and other SARS-CoV-2 variants of concernSemantic proximity Read

SARS-CoV-2 B.1.1.7 escape from mRNA vaccine-elicited neutralizing antibodiesSemantic proximity Read

COVID-19 mRNA vaccine induced antibody responses and neutralizing antibodies against three SARS-CoV-2 variantsSemantic proximity Read

Variants of SARS-CoV-2, their effects on infection, transmission and neutralization by vaccine-induced antibodies.Semantic proximity Read

SARS-CoV-2 spike variants exhibit differential infectivity and neutralization resistance to convalescent or post-vaccination sera.Semantic proximity Read

SARS-CoV-2 immune evasion by variant B.1.427/B.1.429Semantic proximity Read

Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.Semantic proximity Read

SARS-COV-2 Recombinant Receptor-Binding-Domain (RBD) Induces Neutralising Antibodies Against Variant Strains of SARS-CoV-2 and SARS-CoV-1Semantic proximity Read

Potent neutralization of SARS-CoV-2 variants by RBD nanoparticle and prefusion-stabilized spike immunogensSemantic proximity Read

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity.Semantic proximity Read