Article
[Detection of BRAF V600E mutation in metastatic colorectal carcinoma : A QuIP round robin test].
Der Pathologe - 1 Mar 2022
Jöhrens Korinna, Fischer Josephine, Möbs Markus, Junker Klaus, Kirfel Jutta, Perner Sven, Laßmann Silke, Werner Martin, Borgmann Vanessa, Bläker Hendrik, Hummel Michael
Abstract excerpt
Round robin testing is an important instrument for quality assurance. Increasingly, this also applies to the results of molecular diagnostics in pathology, which directly influence therapy decisions in precision oncology. In metastatic colorectal carcinoma (mCRC), the focus has been on detecting KRAS and NRAS mutations, whose absence allows therapy with EGFR blocking antibodies. Recently, BRAF has been added as...
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