Article
Evaluation of RAS mutational status through BEAMing assay to monitor disease progression of metastatic colorectal cancer: a case report.
Anti-cancer drugs - 1 Oct 2020
Lastraioli Elena, Lavacchi Daniele, Palmieri Valeria Emma, Castiglione Francesca, Messerini Luca, Di Costanzo Francesco, Antonuzzo Lorenzo
Abstract excerpt
Since the introduction of antiepidermal growth factor receptor (anti-EGFR) monoclonal antibodies (moAbs), the treatment of metastatic colorectal cancer (mCRC) has become crucially dependent on the mutation profile of the tumour over the last two decades. Recently, rechallenge strategy with cetuximab-based chemotherapy has demonstrated to be active in a subgroup of patients whose tumour maintained wild-type RAS...
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