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Article

[BRAF-V600E testing in metastatic colorectal cancer and new, chemotherapy-free therapy options. German version].

Der Pathologe - 1 Nov 2021

Hummel Michael, Hegewisch-Becker Susanna, Neumann Jens, Vogel Arndt

Abstract excerpt

In the past 25 years, treatment of metastatic colorectal cancer (mCRC) has undergone profound changes. The approval of newer chemotherapeutics such as irinotecan and oxaliplatin was followed in 2005 by the first targeted therapies, for example, monoclonal antibodies directed against the epidermal growth factor receptor (EGFR), as cetuximab and panitumumab, or the angiogenesis inhibitors bevacizumab, ramucirumab,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33956173
DOI: 10.1007/s00292-021-00942-9
PMCID: PMC8536591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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