Article
AGER gene variant as a risk factor for juvenile idiopathic arthritis.
The journal of gene medicine - 1 Feb 2022
Bakutenko Ivan Yurievich, Haurylchyk Irena Dmitrievna, Sechko Elena Vladimirovna, Tchitchko Alexei Mihajlovich, Batyan Galina Mihajlovna, Sukalo Alexander Vasil'evich, Ryabokon Nadezhda Ivanovna
Abstract excerpt
BACKGROUND: The AGER gene encodes a cell surface multiligand receptor of advanced glycation end-products that is also capable of binding other molecules and is involved in numerous pathways related to inflammation, apoptosis, immunity and so on. In the present study, we aimed to investigate whether the AGER rs1035798 (G>A) intronic polymorphism, showing an association with multiple sclerosis and rheumatoid...
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