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Ten Reasons Why People With Down Syndrome are Protected From the Development of Most Solid Tumors -A Review

5 Nov 2021

Abstract excerpt

People with Down syndrome have unique characteristics as a result of the presence of an extra chromosome 21. Regarding cancer, they present a unique pattern of tumors, which has not been fully explained to date. Globally, people with Down syndrome have a similar lifetime risk of developing cancer compared to the general population. However, they have a very increased risk of developing certain tumors (e.g., acute...

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PMID: 34804119
DOI: 10.3389/fgene.2021.749480

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