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Article

Preimplantation genetic diagnosis for mitochondrial DNA disorders: ethical guidance for clinical practice.

European journal of human genetics : EJHG - 1 Dec 2009

Bredenoord Annelien, Dondorp Wybo, Pennings Guido, de Die-Smulders Christine, Smeets Bert, de Wert Guido

Abstract excerpt

Although morally acceptable in theory, preimplantation genetic diagnosis (PGD) for mitochondrial DNA (mtDNA) disorders raises several ethical questions in clinical practice. This paper discusses the major conditions for good clinical practice. Our starting point is that PGD for mtDNA mutations should as far as possible be embedded in a scientific research protocol. For every clinical application of PGD for mtDNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19471315
DOI: 10.1038/ejhg.2009.88
PMCID: PMC2987024

Genes

PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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