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Article

DPF3, A Putative Candidate Gene For Melanoma Etiopathogenesis in Gray Horses.

Journal of equine veterinary science - 1 Jan 2022

Druml Thomas, Brem Gottfried, Horna Michaela, Ricard Anne, Grilz-Seger Gertrud

Abstract excerpt

Melanoma prevalence in gray horses reaches up to 50% and more. Several studies have documented a genetic melanoma predisposition which is referred to the 4.6 kb duplication in intron 6 of STX17 and its surrounding haplotype. However, the genetic background and mechanisms responsible for differences in etiopathogenesis of equine dermal melanomatosis still remain unknown. In the current study, we performed a genome...

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PMID: 34801788
DOI: 10.1016/j.jevs.2021.103797

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