Article
Coat color genotypes and risk and severity of melanoma in gray quarter horses.
Journal of veterinary internal medicine - 1 Jan 2000
Teixeira R B C, Rendahl A K, Anderson S M, Mickelson J R, Sigler D, Buchanan B R, Coleman R J, McCue M E
Abstract excerpt
BACKGROUND: Both graying and melanoma formation in horses have recently been linked to a duplication in the STX17 gene. This duplication, as well as a mutation in the ASIP gene that increases MC1R pathway signaling, affects melanoma risk and severity in gray horses. OBJECTIVE: To determine if melanoma susceptibility in gray Quarter Horses (QH) is lower than gray horses from other breeds because of decreased MC1R...
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