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Article

Genes involved in the WNT and vesicular trafficking pathways are associated with melanoma predisposition.

International journal of cancer - 1 May 2015

Ibarrola-Villava Maider, Kumar Rajiv, Nagore Eduardo, Benfodda Meriem, Guedj Mickael, Gazal Steven, Hu Hui-Han, Guan Jian, Rachkonda P Sivaramakishna, Descamps Vincent, Basset-Seguin Nicole, Bensussan Armand, Bagot Martine, Saiag Philippe, Schadendorf Dirk, Martin-Gonzalez Manuel, Mayor Matias, Grandchamp Bernard, Ribas Gloria, Soufir Nadem

Abstract excerpt

Multifactorial predisposition to melanoma includes genes involved in pigmentation, immunity and DNA repair. Nonetheless, missing heritability in melanoma is still important. We studied the role of 335 candidate SNPs in melanoma susceptibility by using a dedicated chip and investigating 110 genes involved in different pathways. A discovery set was comprised of 1069 melanoma patients and 925 controls from France....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25303718
DOI: 10.1002/ijc.29257

Genes

VPS41
WNT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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