Article
Two Novel Variants in MITF and PAX3 Associated With Splashed White Phenotypes in Horses.
Journal of equine veterinary science - 1 Sept 2023
McFadden Aiden, Martin Katie, Foster Gabriel, Vierra Micaela, Lundquist Erica W, Everts Robin E, Martin Erik, Volz Erin, McLoone Kaitlyn, Brooks Samantha A, Lafayette Christa
Abstract excerpt
Mutations causing depigmentation are relatively common in Equus caballus (horse). Over 40 alleles in multiple genes are associated with increased white spotting (as of February 2023). The splashed white phenotype, a coat spotting pattern described as appearing like the horse has been splashed with white paint, was previously associated with variants in the PAX3 and MITF genes. Both genes encode transcription...
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