Article
Equine vitiligo-like depigmentation in grey horses is related to genes involved in immune response and tumor metastasis.
BMC veterinary research - 25 Oct 2021
Druml Thomas, Brem Gottfried, Velie Brandon, Lindgren Gabriella, Horna Michaela, Ricard Anne, Grilz-Seger Gertrud
Abstract excerpt
BACKGROUND: In horses, the autoimmune disease vitiligo is characterized by the loss of melanocytes and results in patchy depigmentation of the skin around the eyes, muzzle and the perianal region. Vitiligo-like depigmentation occurs predominantly in horses displaying the grey coat colour and is observed at a prevalence level of 26.0-67.0% in grey horses compared with only 0.8-3.5% in non-grey horses. While the...
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