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Article

Capturing hidden regulation based on noise change of gene expression level from single cell RNA-seq in yeast.

Scientific reports - 19 Nov 2021

Itoh Thoma, Makino Takashi

Abstract excerpt

Recent progress in high throughput single cell RNA-seq (scRNA-seq) has activated the development of data-driven inferring methods of gene regulatory networks. Most network estimations assume that perturbations produce downstream effects. However, the effects of gene perturbations are sometimes compensated by a gene with redundant functionality (functional compensation). In order to avoid functional compensation,...

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Identifiers

PMID: 34799619
DOI: 10.1038/s41598-021-01558-y
PMCID: PMC8604932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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