Article
Cyclophilin acts as a ribosome biogenesis factor by chaperoning the ribosomal protein (PlRPS15) in filamentous fungi.
Nucleic acids research - 2 Dec 2021
Mo Chenmi, Xie Chong, Wang Gaofeng, Tian Tian, Liu Juan, Zhu Chunxiao, Xiao Xueqiong, Xiao Yannong
Abstract excerpt
The rapid transport of ribosomal proteins (RPs) into the nucleus and their efficient assembly into pre-ribosomal particles are prerequisites for ribosome biogenesis. Proteins that act as dedicated chaperones for RPs to maintain their stability and facilitate their assembly have not been identified in filamentous fungi. PlCYP5 is a nuclear cyclophilin in the nematophagous fungus Purpureocillium lilacinum, whose...
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