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Article

Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome.

Molecular biology of the cell - 1 Apr 2011

Yu Zanlin, Kleifeld Oded, Lande-Atir Avigail, Bsoul Maisa, Kleiman Maya, Krutauz Daria, Book Adam, Vierstra Richard D, Hofmann Kay, Reis Noa, Glickman Michael H, Pick Elah

Abstract excerpt

Subunit composition and architectural structure of the 26S proteasome lid is strictly conserved between all eukaryotes. This eight-subunit complex bears high similarity to the eukaryotic translation initiation factor 3 and to the COP9 signalosome (CSN), which together define the proteasome CSN/COP9/initiation factor (PCI) troika. In some unicellular eukaryotes, the latter two complexes lack key subunits,...

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Identifiers

PMID: 21289098
DOI: 10.1091/mbc.E10-08-0655
PMCID: PMC3069016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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