Article
A Possible Sterilizing Cure of HIV-1 Infection Without Stem Cell Transplantation.
Annals of internal medicine - 1 Jan 2022
Turk Gabriela, Seiger Kyra, Lian Xiaodong, Sun Weiwei, Parsons Elizabeth M, Gao Ce, Rassadkina Yelizaveta, Polo Maria Laura, Czernikier Alejandro, Ghiglione Yanina, Vellicce Alejandra, Varriale Joseph, Lai Jun, Yuki Yuko, Martin Maureen, Rhodes Ajantha, Lewin Sharon R, Walker Bruce D, Carrington Mary, Siliciano Robert, Siliciano Janet, Lichterfeld Mathias, Laufer Natalia, Yu Xu G
Abstract excerpt
BACKGROUND: A sterilizing cure of HIV-1 infection has been reported in 2 persons living with HIV-1 who underwent allogeneic hematopoietic stem cell transplantations from donors who were homozygous for the CCR5Δ32 gene polymorphism. However, this has been considered elusive during natural infection. OBJECTIVE: To evaluate persistent HIV-1 reservoir cells in an elite controller with undetectable HIV-1 viremia for...
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