Article
Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors.
Journal of virology - 1 Mar 2007
Blankson Joel N, Bailey Justin R, Thayil Seema, Yang Hung-Chih, Lassen Kara, Lai Jun, Gandhi Shiv K, Siliciano Janet D, Williams Thomas M, Siliciano Robert F
Abstract excerpt
Elite suppressors (ES) are untreated human immunodeficiency virus type 1 (HIV-1)-infected individuals who control viremia to levels below the limit of detection of current assays. The mechanisms involved in this control have not been fully elucidated. Several studies have demonstrated that some ES are infected with defective viruses, but it remains unclear whether others are infected with replication-competent...
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