Article
Delayed-onset enzootic bovine leukosis possibly caused by superinfection with bovine leukemia virus mutated in the pol gene.
Archives of virology - 1 Aug 2015
Watanabe Tadaaki, Inoue Emi, Mori Hiroshi, Osawa Yoshiaki, Okazaki Katsunori
Abstract excerpt
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leucosis (EBL), to which animals are most susceptible at 4-8 years of age. In this study, we examined tumor cells associated with EBL in an 18-year-old cow to reveal that the cells carried at least two different copies of the virus, one of which was predicted to encode a reverse transcriptase (RT) lacking ribonuclease H activity and no...
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