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Article

Association of TNF-α G-308 a Promoter Polymorphism with the Course and Outcome of COVID-19 Patients.

Immunological investigations - 1 Apr 2022

Saleh Ahmed, Sultan Ahmed, Elashry Mohamed A, Farag Ahmed, Mortada Metwaly Ibrahim, Ghannam Mayada A, Saed Ahmed M, Ghoneem Elsayed

Abstract excerpt

BACKGROUND: Tumor necrosis factor-ɑ (TNF-ɑ) is one of the most important cytokines that manage the host defense mechanism, which may play a role in the pathogenesis of COVID-19 patients. The work aims to study the association of TNF-ɑ G-308 A gene polymorphism with the course and outcome of COVID-19 patients in Mansoura University Hospital. METHODS: 900 patients with COVID-19 infection and 184 controls were...

Topics

COVID-19
Case-Control Studies
Genetic Predisposition to Disease
Genotype
Humans
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
Tumor Necrosis Factor-alpha

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open in PubMed Open full text

Identifiers

PMID: 33228423
DOI: 10.1080/08820139.2020.1851709
PMCID: PMC7711738

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-33228423-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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