Article
Status of APOBEC3G/F in cells and progeny virions modulated by Vif determines HIV-1 infectivity.
Microbes and infection - 1 Feb 2010
Yamashita Tomoki, Nomaguchi Masako, Miyake Ariko, Uchiyama Tsuneo, Adachi Akio
Abstract excerpt
We examined various HIV-1 Vif mutants for interaction with APOBEC3 proteins (A3G/A3F). All replication-defective proviral mutants were found to carry A3G/A3F in virions, and of these, a replication-defective mutant with Vif that binds to A3G in cells but not in virions was noted. Furthermore, a m...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
