Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Age-dependent prognostic value of KRAS mutation in metastatic colorectal cancer.

Future oncology (London, England) - 1 Dec 2021

Ozer Muhammet, Goksu Suleyman Yasin, Sanford Nina Niu, Ahn Chul, Beg Muhammad Shaalan, Ali Kazmi Syed Mohammad

Abstract excerpt

Background: The age-dependent prognostic impact of KRAS status in metastatic colorectal cancer (mCRC) is unknown. Materials & Methods: We used the National Cancer Database to evaluate the survival by KRAS status for age-groups <50, 50-69 and ≥70, adjusting for relevant patient and tumor characteristics. Results: mCRC patients (n = 26,095; 33.5%) had KRAS status reported, and 11,338 of these patients (43.4%) had...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Combined Modality Therapy

Share to Comorbidity

Share to Neoplasm Staging

Share to Proto-Oncogene Proteins p21(ras)

Share to Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 34758634
DOI: 10.2217/fon-2021-0650
PMCID: PMC8890131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Age-dependent prognostic value of KRAS mutation in metastatic colorectal cancer.PMID 34758634Read ↗

Predictive and prognostic value of KRAS mutations in metastatic colorectal cancer patients treated with cetuximab: a meta-analysis of 22 studies.Semantic proximity Read ↗

Clinical and prognostic implications of RAS mutations in metastatic colorectal cancer.Semantic proximity Read ↗

Prognostic and predictive value of KRAS mutation number in metastatic colorectal cancer.Semantic proximity Read ↗

Impact of KRAS mutation on outcome of patients with metastatic colorectal cancer.Semantic proximity Read ↗

The association of clinicopathological features and survival in colorectal cancer patients with kras mutation status.Semantic proximity Read ↗

KRAS Sequence Variation as Prognostic Marker in Patients With Young- vs Late-Onset Colorectal CancerSemantic proximity Read ↗

Prognostic Value of KRAS Gene Mutation on Survival of Patients with Peritoneal Metastases of Colorectal Adenocarcinoma.Semantic proximity Read ↗

BRAF Mutations Are Associated with Poor Survival Outcomes in Advanced-stage Mismatch Repair-deficient/Microsatellite High Colorectal Cancer.Semantic proximity Read ↗

Activating KRAS mutation is prognostic only among patients who receive preoperative chemotherapy before resection of colorectal liver metastases.Semantic proximity Read ↗

Association of KRAS G12C Status with Age at Onset of Metastatic Colorectal CancerSemantic proximity Read ↗

The prognostic impact of RAS on overall survival following liver resection in early versus late-onset colorectal cancer patients.Semantic proximity Read ↗

Association between KRAS mutation and lung metastasis in advanced colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.