Article
Association between KRAS mutation and lung metastasis in advanced colorectal cancer.
British journal of cancer - 3 Feb 2015
Pereira A A L, Rego J F M, Morris V, Overman M J, Eng C, Garrett C R, Boutin A T, Ferrarotto R, Lee M, Jiang Z-Q, Hoff P M, Vauthey J-N, Vilar E, Maru D, Kopetz S
Abstract excerpt
BACKGROUND: KRAS mutations have been associated with lung metastases at diagnosis of metastatic colorectal cancer (mCRC), but the impact of this mutation on subsequent development of lung metastasis is unknown. We investigated KRAS mutation as a predictor of lung metastasis development. METHODS: We retrospectively evaluated data from patients with mCRC whose tumour was tested for KRAS mutation from 2008 to 2010....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.