Prospective molecular classification of endometrial carcinomas: institutional implementation, practice, and clinical experience.

doi:10.1038/s41379-021-00963-y

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Prospective molecular classification of endometrial carcinomas: institutional implementation, practice, and clinical experience.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2022

Devereaux Kelly A, Weiel Julianna J, Pors Jennifer, Steiner David F, Ho Chandler, Charu Vivek, Suarez Carlos J, Renz Malte, Diver Elisabeth, Karam Amer, Litkouhi Babak, Dorigo Oliver, Kidd Elizabeth A, Yang Eric J, Folkins Ann K, Longacre Teri A, Howitt Brooke E

Abstract excerpt

The comprehensive genomic analysis of endometrial carcinoma (EC) by The Cancer Genome Atlas (TCGA) led to the discovery of four distinct and prognostically significant molecular subgroups. Molecular classification has the potential to improve risk-stratification when integrated with clinicopathologic features and has recently been included in national and international patient management EC guidelines. Thus, the...

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PMID: 34743187
DOI: 10.1038/s41379-021-00963-y

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