Article
Confirmation of ProMisE: A simple, genomics-based clinical classifier for endometrial cancer.
Cancer - 1 Mar 2017
Talhouk Aline, McConechy Melissa K, Leung Samuel, Yang Winnie, Lum Amy, Senz Janine, Boyd Niki, Pike Judith, Anglesio Michael, Kwon Janice S, Karnezis Anthony N, Huntsman David G, Gilks C Blake, McAlpine Jessica N
Abstract excerpt
BACKGROUND: Classification of endometrial carcinomas (ECs) by morphologic features is irreproducible and imperfectly reflects tumor biology. The authors developed the Proactive Molecular Risk Classifier for Endometrial Cancer (ProMisE), a molecular classification system based on The Cancer Genome Atlas genomic subgroups, and sought to confirm both feasibility and prognostic ability in a new, large cohort of ECs....
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