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Article

Selection of HIV Envelope Strains for Standardized Assessments of Vaccine-Elicited Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies.

Journal of virology - 26 Jan 2022

Mielke Dieter, Stanfield-Oakley Sherry, Borate Bhavesh, Fisher Leigh H, Faircloth Katelyn, Tuyishime Marina, Greene Kelli, Gao Hongmei, Williamson Carolyn, Morris Lynn, Ochsenbauer Christina, Tomaras Georgia, Haynes Barton F, Montefiori David, Pollara Justin, deCamp Allan C, Ferrari Guido

Abstract excerpt

Antibody-dependent cellular cytotoxicity (ADCC) has been correlated with reduced risk of human immunodeficiency virus type 1 (HIV-1) infection in several preclinical vaccine trials and in the RV144 clinical trial, indicating that this is a relevant antibody function to study. Given the diversity of HIV-1, the breadth of vaccine-induced antibody responses is a critical parameter to understand if a universal...

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Share to AIDS Vaccines
Share to Antibodies, Neutralizing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibody-Dependent Cell Cytotoxicity

Share to env Gene Products, Human Immunodeficiency Virus

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Share to HIV Infections

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Identifiers

PMID: 34730393
DOI: 10.1128/JVI.01643-21
PMCID: PMC8791251

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