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Role of HIV-1 Envelope Glycoproteins Conformation and Accessory Proteins on ADCC Responses

27 Aug 2015

Abstract excerpt

The role of antibody Fc-mediated effector functions in controlling or preventing infections by human immunodeficiency type 1 (HIV-1) and simian immunodeficiency (SIV) viruses has been recently highlighted in multiple studies. One of those effector functions, antibody-dependent cellular cytotoxicity (ADCC) was suggested as correlating with decreased HIV-1 acquisition risk in the recent Thai RV144 vaccine trial....

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PMID: 26310828
DOI: 10.2174/1570162x13666150827093449

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