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Article

Breadth of HIV-1 Env-specific antibody-dependent cellular cytotoxicity: relevance to global HIV vaccine design.

AIDS (London, England) - 24 Aug 2014

Madhavi Vijaya, Wren Leia H, Center Rob J, Gonelli Christopher, Winnall Wendy R, Parsons Matthew S, Kramski Marit, Kent Stephen J, Stratov Ivan

Abstract excerpt

OBJECTIVE: The objective of this study is to determine the breadth of HIV-1 Env-specific antibody-dependent cellular cytotoxicity (ADCC) in HIV controllers and HIV progressors with a view to design globally relevant HIV vaccines. DESIGN: The breadth of ADCC towards four major HIV-1 Env subtypes was measured in vitro for 11 HIV controllers and 11 HIV progressors. METHODS: Plasma from 11 HIV controllers (including...

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Identifiers

PMID: 24937308
DOI: 10.1097/QAD.0000000000000310

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