Article

The role of cervical reserve cells in epithelial regeneration and homeostasis in the murine and human cervix

2021-01-01

Abstract excerpt

How cervical epithelium maintains homeostasis and repair, and how the high-risk human papilloma viruses (HR-HPV) drive neoplasia at the cervical transformation zone (TZ) has been poorly researched. The cervical TZ is thought to be a stem cell niche as it harbours a unique cell population called reserve cells. Reserve cells (marked by KRT17) are believed to have a dual fate ability depending on local microenvironme...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5df99248-7794-5d83-8419-3f4e27c44a7d
DOI: 10.17863/cam.75317

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The role of cervical reserve cells in epithelial regeneration and homeostasis in the murine and human cervixDOI 10.17863/cam.75317Read

Role of Reserve Cells in Metaplasia and the Development of Human Papillomavirus–Associated High-Grade Squamous Intraepithelial Lesions at the Cervical Transformation ZoneSemantic proximity Read

Establishment and optimization of epithelial cell cultures from human ectocervix, transformation zone, and endocervix optimization of epithelial cell culturesSemantic proximity Read

Single-cell analysis defines the lineage plasticity of stem cells in cervix epitheliumSemantic proximity Read

Regulation and Deregulation of Viral Gene Expression During High-Risk HPV InfectionSemantic proximity Read

Establishment and Molecular Phenotyping of Organoids from the Squamocolumnar Junction Region of the Uterine CervixSemantic proximity Read

Microbial metabolites control self-renewal and precancerous progression of human cervical stem cellsSemantic proximity Read

Human Papillomavirus Infections and Cancer Stem Cells of Tumors from the Uterine CervixSemantic proximity Read

Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancerSemantic proximity Read

Principles of epithelial homeostasis control during persistent human papillomavirus infection and its deregulation at the cervical transformation zoneSemantic proximity Read

Cervical cancer stem cells: opportunities and challengesSemantic proximity Read

Contemporary theories of cervical carcinogenesis: the virus, the host, and the stem cell.Semantic proximity Read

A novel blueprint for ‘top down’ differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasiaSemantic proximity Read