Single-cell RNA sequencing and lineage tracing confirm mesenchyme to epithelial transformation (MET) contributes to repair of the endometrium at menstruation

Abstract excerpt

The human endometrium experiences repetitive cycles of tissue wounding characterised by piecemeal shedding of the surface epithelium and rapid restoration of tissue homeostasis. In this study, we used a mouse model of endometrial repair and three transgenic lines of mice to investigate whether epithelial cells that become incorporated into the newly formed luminal epithelium have their origins in one or more of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Endometrial and Cervical Cancer Treatments
• Share to Endometriosis Research and Treatment
• Share to Reproductive System and Pregnancy