Article
LocalNgsRelate: a software tool for inferring IBD sharing along the genome between pairs of individuals from low-depth NGS data.
Bioinformatics (Oxford, England) - 27 Jan 2022
Severson Alissa L, Korneliussen Thorfinn Sand, Moltke Ida
Abstract excerpt
MOTIVATION: Inference of identity-by-descent (IBD) sharing along the genome between pairs of individuals has important uses. But all existing inference methods are based on genotypes, which is not ideal for low-depth Next Generation Sequencing (NGS) data from which genotypes can only be called with high uncertainty. RESULTS: We present a new probabilistic software tool, LocalNgsRelate, for inferring IBD sharing...
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