Article
Benchmarking kinship estimation tools for ancient genomes using pedigree simulations.
Molecular ecology resources - 1 Jul 2024
Aktürk Şevval, Mapelli Igor, Güler Merve N, Gürün Kanat, Katırcıoğlu Büşra, Vural Kıvılcım Başak, Sağlıcan Ekin, Çetin Mehmet, Yaka Reyhan, Sürer Elif, Atağ Gözde, Çokoğlu Sevim Seda, Sevkar Arda, Altınışık N Ezgi, Koptekin Dilek, Somel Mehmet
Abstract excerpt
There is growing interest in uncovering genetic kinship patterns in past societies using low-coverage palaeogenomes. Here, we benchmark four tools for kinship estimation with such data: lcMLkin, NgsRelate, KIN, and READ, which differ in their input, IBD estimation methods, and statistical approaches. We used pedigree and ancient genome sequence simulations to evaluate these tools when only a limited number (1 to...
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