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Gene code CD274/PD-L1 : from molecular basis toward cancer immunotherapy

1 Jan 2018

Abstract excerpt

The programmed death 1 receptor (PD-1) and its ligand (PD-L1) are key molecules of immune checkpoint mechanisms in cancer and actually represent one of the main targets of immunotherapy. The predictive and prognostic values of PD-L1 expression alone in cancer patients is currently under debate due to the methodological assessment of PD-L1 expression and its temporal variations. Better detailed studies about the...

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PMID: 30574211
DOI: 10.1177/1758835918815598

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