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Article

Endoplasmic reticulum stress in human photoreceptor diseases.

Brain research - 1 Oct 2016

Chan Priscilla, Stolz Julia, Kohl Susanne, Chiang Wei-Chieh, Lin Jonathan H

Abstract excerpt

Photoreceptors are specialized sensory neurons essential for light detection in the human eye. Photoreceptor cell dysfunction and death cause vision loss in many eye diseases such as retinitis pigmentosa and achromatopsia. Endoplasmic reticulum (ER) stress and Unfolded Protein Response (UPR) signaling have been implicated in the development and pathology of heritable forms of retinitis pigmentosa and...

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Share to Activating Transcription Factor 6
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Share to ATF6 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to RHO gene

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Share to Photoreceptor Cells, Vertebrate

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Source

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Identifiers

PMID: 27117871
DOI: 10.1016/j.brainres.2016.04.021
PMCID: PMC5036988

Genes

ATF6
RHO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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