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Article

Interleukin enhancer‐binding factor 2 promotes cell proliferation and DNA damage response in metastatic melanoma

1 Oct 2021

Abstract excerpt

BACKGROUND: 1q21.3 amplification, which is frequently observed in metastatic melanoma, is associated with cancer progression. Interleukin enhancer-binding factor 2 (ILF2) is located in the 1q21.3 amplified region, but its functional role or contribution to tumour aggressiveness in cutaneous melanoma is unknown. METHODS: In silico analyses were performed using the TCGA SKCM dataset with clinical annotations and...

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PMID: 34709752
DOI: 10.1002/ctm2.608

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