Article
The Expression Quantitative Trait Loci in Immune Pathways and their Effect on Cutaneous Melanoma Prognosis.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2016
Vogelsang Matjaz, Martinez Carlos N, Rendleman Justin, Bapodra Anuj, Malecek Karolina, Romanchuk Artur, Kazlow Esther, Shapiro Richard L, Berman Russell S, Krogsgaard Michelle, Osman Iman, Kirchhoff Tomas
Abstract excerpt
PURPOSE: The identification of personalized germline markers with biologic relevance for the prediction of cutaneous melanoma prognosis is highly demanded but to date, it has been largely unsuccessful. As melanoma progression is controlled by host immunity, here we present a novel approach interrogating immunoregulatory pathways using the genome-wide maps of expression quantitative trait loci (eQTL) to reveal...
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