Article
The Role of RASs /RVs in the Current Management of HCV.
Viruses - 18 Oct 2021
Malandris Konstantinos, Kalopitas Georgios, Theocharidou Eleni, Germanidis Georgios
Abstract excerpt
The approval of combination therapies with direct-acting antiviral (DAA) regimens has led to significant progress in the field of hepatitis C virus (HCV) treatment. Although most patients treated with these agents achieve a virological cure, resistance to DAAs is a major issue. The rapid emergence of resistance-associated substitutions (RASs), in particular in the context of incomplete drug pressure, has an...
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