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Directly acting antivirals against hepatitis C virus: mechanisms of action and impact of resistant associated variants.

Minerva gastroenterologica e dietologica - 1 Mar 2016

Premoli Caterina, Aghemo Alessio

Abstract excerpt

Hepatitis C virus (HCV) drug development has resulted in interferon-free (IFN) regimens of direct-acting antivirals (DAAs). The new therapies are highly effective achieving 90-95% of sustained virologic response (SVR) rates among all genotypes with minimal treatment-related side effects. They opened a new scenario in HCV treatment representing a treatment option for patients who were ineligible to IFN-based...

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PMID: 26448306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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