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Article

Human genetic polymorphisms and risk of viral infection after solid organ transplantation.

Transplantation reviews (Orlando, Fla.) - 1 Jan 2022

Redondo Natalia, Navarro David, Aguado José María, Fernández-Ruiz Mario

Abstract excerpt

The immune system plays a key role in the host defense against viral pathogens. A signaling cascade is activated upon infection involving a variety of molecules such as pattern-recognition receptors (PRRs), interleukins or antiviral interferons. Long-term immunosuppression after solid organ transplantation (SOT) mainly abrogates adaptive T-cell-mediated responses, thus highlighting the relative contribution of...

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Identifiers

PMID: 34688126
DOI: 10.1016/j.trre.2021.100669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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