Article
CTLA4 Single-Nucleotide Polymorphisms Influence the Risk of HSV and VZV Infection in Kidney Transplant Recipients: A Prospective Cohort Study.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Jan 2025
Redondo Natalia, Rodríguez-Goncer Isabel, Ruiz-Merlo Tamara, López-Medrano Francisco, González Esther, Polanco Natalia, Hernández-Vicente Ana, San Juan Rafael, Andrés Amado, Aguado José María, Fernández-Ruiz Mario
Abstract excerpt
Herpesviruses are able to modulate adaptive T-cell-mediated responses to establish latency within the host. Reactivation of herpes simplex virus (HSV)-1/2 and varicella zoster virus (VZV) is a frequent and potentially serious complication among kidney transplant recipients (KTRs). The ability of clinical criteria to identify KTRs at increased risk of α-herpesvirus (HSV/VZV) infection is limited. We investigated...
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