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Article

Genetic polymorphisms in TLR3, IL10 and CD209 influence the risk of BK polyomavirus infection after kidney transplantation.

Scientific reports - 5 Jul 2022

Redondo Natalia, Rodríguez-Goncer Isabel, Parra Patricia, López-Medrano Francisco, González Esther, Hernández Ana, Trujillo Hernando, Ruiz-Merlo Tamara, San Juan Rafael, Folgueira María Dolores, Andrés Amado, Aguado José María, Fernández-Ruiz Mario

Abstract excerpt

Genetic determinants of BK polyomavirus infection after kidney transplantation remain poorly investigated. We assessed the potential impact of 13 different single nucleotide polymorphisms within genes mainly involved in innate immune responses on the risk of BKPyV viremia in 204 KT recipients. After a median follow-up of 1121.5 days, the cumulative incidence of any-level BKPyV viremia was 24.5% (50/204). There...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35790769
DOI: 10.1038/s41598-022-15406-0
PMCID: PMC9255529

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