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Multiple Mutation Detection for Risk Assessment in Patients with Breast Cancer by Using Next-Generation Sequencing.

Annals of clinical and laboratory science - 1 Sept 2021

Liu Peng-Fei, Zhuo Zhong-Ling, Xie Fei, Xian Hai-Peng, Liu Chang, Wang Shu, Zhao Xiao-Tao

Abstract excerpt

OBJECTIVE: Breast cancer is recognized as the most common cause of malignancy and cancer death worldwide; however, mutations in the cancer-related BRCA genes are detected in only 2-3% of patients with breast cancer. Because next-generation sequencing technology allows concurrent sequencing of numerous target genes, diverse cancer-susceptibility genes are now being evaluated, although their significance in...

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PMID: 34686509

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