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Article

Comparative Mutational Profiling of Hematopoietic Progenitor Cells and Circulating Endothelial Cells (CECs) in Patients with Primary Myelofibrosis.

Cells - 15 Oct 2021

Farina Mirko, Bernardi Simona, Polverelli Nicola, D'Adda Mariella, Malagola Michele, Bosio Katia, Re Federica, Almici Camillo, Dunbar Andrew, Levine Ross L, Russo Domenico

Abstract excerpt

A role of endothelial cells (ECs) in Primary Myelofibrosis (PMF) was supposed since JAK2 mutation was found in endothelial precursor cells (EPCs) and in ECs captured by laser microdissection. By Cell Search method, the circulating endothelial cells (CECs) from 14 PMF patients and 5 healthy controls have been isolated and compared by NGS with CD34+Hematopoietic stem and progenitors cells (HSPCs) for panel of 54...

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Identifiers

PMID: 34685741
DOI: 10.3390/cells10102764
PMCID: PMC8534986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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