Article

Thrombo-inflammatory endothelial signatures in <i>JAK2</i> -mutated myeloproliferative neoplasms

2026-02-18

Abstract excerpt

<h4>Background</h4> Classical myeloproliferative neoplasms (MPN)—essential thrombocythemia, polycythemia vera, and primary myelofibrosis—are characterized by clonal hematopoiesis, overproduction of mature blood cells, and a high burden of thromboembolic events. Although thrombosis is the leading cause of morbidity and mortality in MPN, the contribution of the vascular endothelium remains incompletely defined. We...

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Literature Corpus work: d4571985-4d1d-5d22-a798-21c01a57072b
DOI: 10.64898/2026.02.16.706250

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