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Study of Early Onset Schizophrenia: Associations of GRIN2A and GRIN2B Polymorphisms

22 Sept 2021

Abstract excerpt

Background: Schizophrenia is a complex mental disorder with a high heritability. Dysfunction of the N-methyl-D-aspartate (NMDA)-type glutamate receptors may be involved in the pathogenesis of schizophrenia. In this study, we examined the contribution of GRIN2A and GRIN2B (Glutamate Ionotropic Receptor NMDA Type Subunit 2A/2B) polymorphisms to the clinical features of schizophrenia, such as the leading symptoms,...

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PMID: 34685369
DOI: 10.3390/life11100997

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