Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk.

doi:10.1002/ajmg.b.31234

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Article

Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2011

Demontis Ditte, Nyegaard Mette, Buttenschøn Henriette N, Hedemand Anne, Pedersen Carsten B, Grove Jakob, Flint Tracey J, Nordentoft Merete, Werge Thomas, Hougaard David M, Sørensen Karina M, Yolken Robert H, Mors Ole, Børglum Anders D, Mortensen Preben Bo

Abstract excerpt

N-methyl-D-aspartate (NMDA) receptors are very important for proper brain development and several lines of evidence support that hypofunction of the NMDA receptors are involved in the pathophysiology of schizophrenia. Gene variation and gene-environmental interactions involving the genes encoding the NMDA receptors are therefore likely to influence the risk of schizophrenia. The aim of this study was to determine...

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Identifiers

PMID: 21919190
DOI: 10.1002/ajmg.b.31234

Genes

GRIN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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