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Article

The Role of Glutamatergic Gene Polymorphisms in the Clinical Phenotypes of Schizophrenia.

Genes - 24 Feb 2023

Poltavskaya Evgeniya G, Kornetova Elena G, Freidin Maxim B, Pozhidaev Ivan V, Paderina Diana Z, Bocharova Anna V, Semke Arkadiy V, Bokhan Nikolay A, Ivanova Svetlana A, Fedorenko Olga Y

Abstract excerpt

BACKGROUND: Personal variations in genetic risk for schizophrenia relate to its phenotypic heterogeneity-both in disorder development and clinical manifestations. Abnormal glutamatergic neurotransmitter system functioning is integrated in the pathogenesis of schizophrenia. METHODS: A sample of 805 Russian schizophrenia patients from the Siberian Federal region was investigated. We examined the association of 39...

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Identifiers

PMID: 36980845
DOI: 10.3390/genes14030575
PMCID: PMC10048659

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